PLPMDB Mutant Example

MUTANT ACCESSION NUMBER: 84
PROTEIN NAME: D-alanine aminotransferase (EC 2.6.1.21) (D-aspartate aminotransferase) (D-amino acid aminotransferase) (D-amino acid transaminase) (DAAT).
SWISS PROT ENTRY: DAAA_BACSP
ORGANISM: BACILLUS SP STRAIN YM-1
GENE NAME: DAT
VARIANT OR MUTAGEN:Mutagen
PMD ENTRY: A981005

MUTATIONS:
POINT Leu 201 Ala

EFFECTS: X-ray crystal structure of the mutant protein complexed with pyridoxal 5''-phosphate (PLP) (PDB accession; 2DAB):X-ray crystal structure of the mutant protein complexed with pyridoxamine 5''-phosphate (PMP) (PDB accession; 1A0G)

REFERENCE:
PUBMED ID: 9749913
TITLE:Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination.
AUTHOR:Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T, Esaki N.
REFERENCE:Protein Eng. 1998 Aug;11(8):613-9.

3D STRUCTURE:1DAA 2DAA 2DAB 4DAA 5DAA