PLPMDB Mutant Example

MUTANT ACCESSION NUMBER: 64
PROTEIN NAME: Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) (AADC) (DOPA decarboxylase) (DDC).
SWISS PROT ENTRY: DDC_RAT
ORGANISM: RATTUS NORVEGICUS RAT
GENE NAME: DDC
VARIANT OR MUTAGEN:Mutagen
PMD ENTRY: A990462

MUTATIONS:
POINT Asp 271 Ala

EFFECTS: Specific activity toward L-dihydroxyphenylalanine (L-DOPA) [0]

REFERENCE:
PUBMED ID: 10584065
TITLE:Structure modelling and site-directed mutagenesis of the rat aromatic L-amino acid pyridoxal 5''-phosphate-dependent decarboxylase: a functional study
AUTHOR:Poupon A, Jebai F, Labesse G, Gros F, Thibault J, Mornon JP, Krieger M.
REFERENCE:Proteins. 1999 Nov 1;37(2):191-203

3D STRUCTURE: Null