PLPMDB Mutant Example

MUTANT ACCESSION NUMBER: 50
PROTEIN NAME: Aspartate aminotransferase (EC 2.6.1.1) (Transaminase A) (ASPAT).
SWISS PROT ENTRY: AAT_ECOLI
ORGANISM: ESCHERICHIA COLI
GENE NAME: ASPC B0928
VARIANT OR MUTAGEN:Mutagen
PMD ENTRY: A951104

MUTATIONS:
POINT Tyr 214 Arg

EFFECTS: Beta-decarboxylase activity [+] (kcat [+]): Aminotransferase activity [-] (kcat [-])

REFERENCE:
PUBMED ID: 7556224
TITLE:Changing the reaction specificity of a pyridoxal-5''-phosphate-dependent enzyme
AUTHOR:Graber R, Kasper P, Malashkevich VN, Sandmeier E, Berger P, Gehring H, Jansonius JN, Christen P.
REFERENCE:Eur J Biochem. 1995 Sep 1;232(2):686-90.

3D STRUCTURE:1AAM 1AAW 1AIA 1AIB 1AIC 1AMQ 1AMR 1AMS 1ARS 1ART 1ASA 1ASB 1ASC 1ASD 1ASE 1ASF 1ASG 1ASL 1ASM 1ASN 1B4X 1BQA 1BQD 1C9C 1CQ6 1CQ7 1CQ8 1CZC 1CZE 1G4V 1G4X 1G7W 1G7X 1IX6 1IX7 1IX8 1QIR 1QIS 1QIT 1SPA 1YOO 2AAT 3AAT 5EAA